Cancer

Researchers from International Agency for Research on Cancer provide details of new studies and findings in the area of cancer

Published in Cancer Weekly, July 24th, 2007

New investigation results, "C620R mutation of the murine ret proto-oncogene: loss of function effect in homozygotes and possible gain of function effect in heterozygotes," are detailed in a study published in International Journal of Cancer. "Germline RET mutations are responsible for different inherited disorders: Hirschsprung disease (congenital aganglionic megacolon), caused by loss of function mutations, familial medullary thyroid carcinoma and multiple endocrine neoplasia type 2, caused by gain of function mutations. Intriguingly, some RET mutations, including C620R, are associated with both types of diseases," scientists writing in the International Journal of Cancer...

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Source: Cancer Weekly (2007-07-24)

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