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Cancer Therapy

New findings from University of Toronto, Toronto Sunnybrook Regional Cancer Center describe advances in cancer therapy

Published in Cancer Weekly, July 24th, 2007

New research, "Dexamethasone for the prophylaxis of radiation-induced pain flare after palliative radiotherapy for bone metastases: a pilot study," is the subject of a report. Researchers in Toronto, Canada conducted a study "To investigate the efficacy of dexamethasone as a prophylactic adjuvant analgesic to decrease pain flare and to assess its safety and tolerance of dexamethasone. Patients treated with a single 8 Gy for bone metastases took 8 mg dexamethasone before the radiation treatment. The Brief Pain Inventory was administered at baseline and then daily for 10 days after radiation."

"Pain flare was defined as a two-point increase in the worst pain or a 25%...

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