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Progen Pharmaceuticals Outlines Preliminary Phase 3 Clinical Trial Design - Patient Enrollment Planned for Second Half of 2007-

Published in Cancer Weekly, July 24th, 2007

Progen Pharmaceuticals Limited (NASDAQ:PGLA) announced key features of its Phase 3 clinical trial design for its anti-cancer treatment for liver cancer, PI-88. The design will allow for a potentially faster and more cost effective trial with a higher likelihood of success than previously reported.

Progen has used key outcomes from its Phase 2 trial and combined input from its Phase 3 Clinical Advisory Board, specialist advisers, and the FDA to design a Phase 3 trial with optimized probability of success. One key design feature of the Phase 3 trial will be the use of disease-free survival (DFS) as a primary endpoint, which reduces the overall cost and timelines...

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