Hepatocellular Cancer

Data on hepatocellular cancer described by researchers at National Defense Medical College, Department of Biochemistry

Published in Cancer Weekly, July 24th, 2007

A new study, "Activation of a system A amino acid transporter, ATA1/SLC38A1, in human hepatocellular carcinoma and preneoplastic liver tissues," is now available. "The expression of amino acid transporter (AT) mRNAs including A system (ATA1/SNAT1/SLC38A1, ATA2/SNAT2/SLC38A2 and ATA3/SNAT3/SLC38A4), L system (LAT1/SLC7A5 and LAT2/SLC7A8), and y+ (CAT2/SLC7A2) genes, were compared among hepatocellular carcinoma (HCC) and non-cancerous liver cells. Among them the ATA1 mRNA expression was significantly elevated in all HCC cell lines (HepG2, HLF, HuH7 and JHH4) examined compared with normal liver tissue," scientists in Saitama, Japan report.

"We further discovered that the...

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Source: Cancer Weekly (2007-07-24)

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