Medical University of Vienna, Department of Clinical Pathology publishes research in thyroid cancer

Data detailed in "Molecular characterization of the desmoplastic tumor stroma in medullary thyroid carcinoma" have been presented. According to recent research from Vienna, Austria, "Medullary thyroid carcinomas are aggressive neoplasias that metastasize very early to loco-regional lymph nodes, and tumors with a desmoplastic stromal reaction have a higher incidence of lymph node metastasis. In order to characterize the desmoplastic response in thyroid cancers, we evaluated the expression pattern of three molecular markers of activated fibroblasts/myofibroblasts, namely, fibroblast activation protein alpha (FAPalpha), tenascin-C (Tn-C), and alpha-smooth muscle actin (alpha-SMA), as well as...

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