Cancer Genetics

Studies from Central South University, Cancer Research Institute have provided new data on cancer genetics

Published in Cancer Weekly, July 31st, 2007

Scientists discuss in "Latent membrane protein 1 encoded by Epstein-Barr virus induces telomerase activity via p16INK4A/Rb/E2F1 and JNK signaling pathways" new findings in cancer. "Elevated telomerase activity is observed in about 90% of human cancers. This activity correlates strictly with human telomerase reverse transcriptase (hTERT)," scientists in Changsha, People's Republic of China report.

"Previously, it was shown that the Epstein-Barr virus-encoded latent membrane protein 1 (LMP1) induced telomerase activity in nasopharyngeal carcinoma cells. In this study, it was indicated that LMP1 inhibited p16(INK4A) expression, promoted phosphorylation of p105 Rb and...

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Source: Cancer Weekly (2007-07-31)

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