Cancer Cell Biology
Reports summarize cancer cell biology research from Case Western Reserve University, CASE Comprehensive Cancer Center
Published in Cancer Weekly, August 7th, 2007
Researchers detail in "Glutathione supplementation potentiates hypoxic apoptosis by S-glutathionylation of p65-NFkappaB," new data in cancer. According to a study from the United States, "In murine embryonic fibroblasts, N-acetyl-L-cysteine (NAC), a GSH generating agent, enhances hypoxic apoptosis by blocking the NFkappaB survival pathway (Qanungo, S., Wang, M., and Nieminen, A. L. (2004) J. Biol. Chem. 279, 50455-50464). Here, we examined sulfhydryl modifications of the p65 subunit of NFkappaB that are responsible for NFkappaB inactivation."
"In MIA PaCa-2 pancreatic cancer cells, hypoxia increased p65-NFkappaB DNA binding and NFkappaB transactivation by 2.6-and...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2007-08-07)
More Articles from Cancer Weekly
- Cancer Gene Therapy
"Preconditioning" Helps Protect Brain's Blood Vessels from Stroke - Cancer Gene Therapy
Pediatric Ritalin Use May Affect Developing Brain - Cancer Vaccines
Gene-Transcription Machinery Seen Poised for Action, Held in Check Until Needed - Bladder Cancer
Pro-Pharmaceuticals Announces Boston Medical Center Dosing Patients with DAVANAT in Advanced Biliary Cancer Trial - Brain Cancer
A Substantial Opportunity Exists for Second-Line Chemotherapy to Enter the Primary Brain Cancer Market - Breast Cancer
American Medical Association Approves CPT Code for Electronic Brachytherapy for Treatment of Early Breast Cancer - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
