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Hepatocellular Cancer Genetics

Findings in hepatocellular cancer genetics reported from University of Hong Kong, Department of Clinical Oncology

Published in Cancer Weekly, August 7th, 2007

Fresh data on hepatocellular cancer are presented in the report "Up-regulation of fibroblast growth factor 3 is associated with tumor metastasis and recurrence in human hepatocellular carcinoma." According to a study from Hong Kong, People's Republic of China, "Recently, we established a hepatocellular carcinoma (HCC) cell line (named H4-M) from a metastatic HCC tumor. In H4-M, a marker chromosome containing a homogeneously staining region (hsr) was identified by cytogenetic analysis."

"The hsr was characterized by chromosome microdissection and the result showed that the hsr was composed of DNA sequence from 11q13. Oncogenes CCND1 and FGF3 were localized within the...

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