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Lung Cancer Therapy

Researchers at Tianjin Medical University, Cancer Institute publish new data on lung cancer therapy

Published in Cancer Weekly, August 7th, 2007

A new study, "CD4 +CD25 + regulatory T cells decreased the antitumor activity of cytokine-induced killer (CIK) cells of lung cancer patients," is now available. According to recent research published in the Journal of Clinical Immunology, "CD(4) (+)CD(25) (+) regulatory T cells (Tregs) have been shown to inhibit cytotoxic lymphocytes-mediated immune responses. Cytokine-induced killer (CIK) cells exert high impact on adoptive immunotherapeutic approaches."

"Therefore, the purpose of this report was to determine the effect of Tregs on CIK cell growth and CIK-induced cytotoxicity for inhibition of tumor growth in vivo as well as in vitro. After depletion of CD(4)...

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