Soft Tissue Sarcoma Therapy
New soft tissue sarcoma therapy research has been reported by scientists at Cross Cancer Institute
Published in Cancer Weekly, August 7th, 2007
A new study, "A phase II and pharmacological study of the matrix metalloproteinase inhibitor (MMPI) COL-3 in patients with advanced soft tissue sarcomas," is now available. "This phase II study evaluated the antitumor activity of the tetracycline analog COL-3, a potent inhibitor of metalloproteinases (MMPs), particularly MMP-2 and MMP-9, on a continuous oral schedule at a dose of 50 mg/m2 daily in patients with advanced and/or metastatic soft tissue sarcoma (STS). The principal endpoints were the rate of objective tumor regression and the proportion of patients who did not experience disease progression during the first 8 weeks of treatment," scientists in Edmonton, Canada report.
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Source: Cancer Weekly (2007-08-07)
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