Cancer Vaccines
Study results from University of Alberta update understanding of cancer vaccines
Published in Cancer Weekly, August 7th, 2007
According to recent research from Edmonton, Canada, "A clinically relevant delivery system that can efficiently target and deliver antigens and adjuvant to dendritic cells (DCs) is under active investigation. Immunization with antigens and immunomodulators encapsulated in poly(D,L-lactic-co-glycolic acid) (PLGA) nanoparticles elicits potent cellular immune responses; but understanding how this mode of delivery affects DCs and priming of naive T cells needs further investigation."
"In the current study, we assessed the extent of maturation of DCs after treatment with monophosphoryl lipid A (MPLA) encapsulated in PLGA nanoparticles and the generation of primary T-cell...
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Source: Cancer Weekly (2007-08-07)
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