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Head and Neck Cancer

Reports on head and neck cancer findings from N. Fuwa and co-researchers provide new insights

Published in Cancer Weekly, August 7th, 2007

According to recent research from Nagoya, Japan, "This study, with a large number of patients, confirms that after administration of 5-fluorouracil (5FU), a higher dose of nedaplatin (NDP) can be safely administered rather than a single therapy of NDP, as demonstrated in a phase I study. The subjects were 52 patients with stage II-IV (M0) head and neck cancer other than nasopharyngeal cancer."

"Alternating chemoradiotherapy was performed using the following method. Initially, chemotherapy was administered. For chemotherapy, 5FU at 700 mg/m(2)/24 h was intravenously administered for 5 days (days 1-5), and NDP was administered on day 6. We established three dose groups:...

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