Breast Cancer
Researchers at University of California, Department of Radiation Oncology publish new data on breast cancer
Published in Cancer Weekly, August 21st, 2007
A new study, "Radiation-induced posttranscriptional control of M6P/IGF2r expression in breast cancer cell lines," is now available. According to recent research published in the journal Molecular Carcinogenesis, "The mannose 6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2r), a member of the IGF axis of growth factors, is a negative regulator of cell growth and a putative tumor suppressor gene. Regulation of M6P/IGF2r levels is critical in breast physiology; low expression is associated with various aspects of breast cancer."
"We have found that ionizing radiation induces the rapid expression of M6P/IGF2r in a dose-dependent manner in MCF7 human breast...
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Source: Cancer Weekly (2007-08-21)
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