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Bladder Cancer

Research from Medical College of Wisconsin, Medical College reveals new findings on bladder cancer

Published in Cancer Weekly, August 21st, 2007

"Work by our group has shown that bacillus Calmette-Guerin (BCG) induces cell cycle arrest at the GUS interface in human transitional carcinoma cell lines. This Study evaluated the effect of BCG oil cell cycle regulatory proteins relevant to this effect. The effect of BCG oil selected cell cycle regulatory proteins, including cyclin D1 p27, and p21, was assessed in 2 human cell lines," researchers in the United States report.

"After the identification of p21 as a candidate protein, p21 regulation was evaluated using a combination of Western, reverse transcriptase polymerase chain reaction, and promoter-reporter analysis. The immediate early versus delayed nature of p21...

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