Cancer
Reports summarize cancer study results from University of Basel
Published in Cancer Weekly, August 21st, 2007
"Although metabolic changes make diagnosis of insulinoma relatively easy, surgical removal is hampered by difficulties in locating it, and there is no efficient treatment for malignant insulinoma. We have previously shown that the high density of glucagon-like peptide-1 receptors (GLP-1R) in human insulinoma cells provides an attractive target for molecular imaging and internal radiotherapy," researchers in Basel, Switzerland report.
"In this study, we investigated the therapeutic potential of [Lys(40)(Ahx-DTPA-(111)ln)NH2]-Exendin-4, an (111)ln-labeled agonist of GLP-1, in a transgenic mouse model of human insulinoma. Experimental [Lys(40)(Ahx-DTPA-(111)ln) NH2]...
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Source: Cancer Weekly (2007-08-21)
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