Cancer
Researchers from Harvard University, Dana-Farber Cancer Institute report on findings in cancer
Published in Cancer Weekly, August 28th, 2007
Data detailed in "Phases of canonical Wnt signaling during the development of mouse intestinal epithelium" have been presented. "Intestinal crypts constitute a niche in which epithelial progenitors respond to Wnt signals, replicate, and prepare to differentiate. Because mutations in Wnt pathway genes lead to intestinal cancer, the role of Wnt signaling in gut epithelial homeostasis is a subject of intense investigation," researchers in the United States report.
"We studied how Wnt signaling is established during intestine development. We studied spatiotemporal features of Wnt signaling at formative stages in mouse embryos, when villous projections appear and crypt...
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Source: Cancer Weekly (2007-08-28)
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