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Cancer Risk Factors

Research from D.M. Proctor and co-researchers in the area of cancer risk factors described

Published in Cancer Weekly, August 28th, 2007

Researchers detail in "Mode-of-action framework for evaluating the relevance of rodent forestomach tumors in cancer risk assessment," new data in cancer. "Studies have shown that a majority of known human carcinogens also cause cancer in laboratory animals. The converse, however, is not as well established-known animal carcinogens are not equally predictive of human carcinogenicity," researchers in the United States report.

"A particularly controversial aspect of interspecies extrapolation is application of rodent forestomach tumor data for predicting cancer risk in humans, given that a human counterpart for the rodent forestomach does not exist. Proliferative lesions...

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