Hepatocellular Cancer Prognosis
Reports from Chang Gung Memorial Hospital, Department of Internal Medicine highlight recent research in hepatocellular cancer prognosis
Published in Cancer Weekly, August 28th, 2007
A report, "P21/WAF1 is an independent survival prognostic factor for patients with hepatocellular carcinoma after resection," is newly published data in Liver International. According to recent research from Kaohsiung, Taiwan, "The cyclin kinase inhibitor p21/WAF1 is regulated by p53-dependent or independent pathways and inhibits the action of proliferating cell nuclear antigen (PCNA). The prognostic role of p21/WAF1 in hepatocellular carcinoma (HCC) is ambiguous."
"To further clarify this, we examined the expression of three genes in HCC. A total of 122 resected HCC specimens were collected from 1987 to 1998. Expression of p21/WAF1, p53, and PCNA in HCC was...
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Source: Cancer Weekly (2007-08-28)
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