Non-Small Cell Lung Cancer Therapy
Research results from Research Institute and Hospital update knowledge of non-small cell lung cancer therapy
Published in Cancer Weekly, August 28th, 2007
Fresh data on non-small cell lung cancer are presented in the report "Associations of ABCB1, ABCC2, and ABCG2 polymorphisms with irinotecan-pharmacokinetics and clinical outcome in patients with advanced non-small cell lung cancer." According to a study from Korea, "The authors investigated whether ABCB1, ABCC2, and ABCG2 genetic polymorphisms affect pharmacokinetics (PK) of irinotecan and treatment outcome of patients with advanced nonsmall cell lung cancer (NSCLC). Blood samples from 107 NSCLC patients treated with irinotecan and cisplatin chemotherapy were used for genotyping ABCB1 (1236C >T, 2677G >T/A, 3435C >T), ABCC2 (-24C >T, 1249G >A, 3972C >T), and ABCG2 (34G...
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Source: Cancer Weekly (2007-08-28)
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