Bioengineering

Findings from S. Forrester and co-authors broaden understanding of bioengineering

Published in Cancer Weekly, August 28th, 2007

"The identification of human tumor antigens has potential utility in the diagnosis and treatment of cancers. We demonstrate here a complete strategy to profile immunoreactivity and identify tumor antigens from proteins derived from tumor cell lines," investigators in the United States report.

"Microarrays of proteins produced from 2-D LC fractionation of prostate tumor cell-line lysates were used to profile immunoreactivity in the sera of prostate cancer patients and control subjects. Cancer-associated immunoreactivity to distinct groups of chromatography fractions was present in about 50% of the patients, with greater immunoreactivity present in patients with...

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Source: Cancer Weekly (2007-08-28)

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