Published in Cancer Weekly, August 28th, 2007
"Spontaneous and radiation-induced mutation rates in homozygous XPc-/- males were significantly higher than those in isogenic wild-type (Xpc(+/+)) and heterozygous (Xpc(+/-)) mice. in contrast, exposure to the monofunctional alkylating agent ethylnitrosourea resulted in similar increases in ESTR mutation rates across all genotypes. ESTR mutation spectra in the germ line of Xpc(-/-),...
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Source: Cancer Weekly (2007-08-28)
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