Colon Cancer

Studies from K. Lekpor et al add new findings in the area of colon cancer

Published in Cancer Weekly, August 28th, 2007

"Multidimensional fingerprinting (MDF) utilizes measurable peptide characteristics to identify proteins. In this study, 3-D fingerprinting, namely, parent protein molecular weight, peptide mass, and peptide retention time on RPLC, is used to identify 331 differentially expressed proteins between normal and human colon cancer plasma membrane samples," scientists in Montreal, Canada report.

"A false discovery rate (FDR) procedure is introduced to evaluate the performance of MDF on the colon cancer dataset. This evaluation establishes a false protein identification rate below 15% for this dataset. Western blot analysis is performed to validate the differential expression...

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Source: Cancer Weekly (2007-08-28)

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