Papillary Cancer

New papillary cancer study results from Oregon Health & Science University described

Published in Cancer Weekly, August 28th, 2007

"The separation of ductal papilloma from intraductal papillary carcinoma of the breast on hematoxylin and eosin stained sections often presents diagnostic difficulty. Immuno-histochemical staining is often employed in diagnosis, historically with smooth muscle actin (SMA)," scientists in the United States report.

"In this study, the staining characteristics of a panel of myoepithelial markers (calponin, p63, P-cadherin), were compared with SMA, and the epithelial expression of CD44s was assessed in 99 papillary lesions. SNIA, calponin, and p63 demonstrated myoepithelial cells in 61%, 63%, and 65% of papillary lesions, respectively. However, specificity was quite...

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Source: Cancer Weekly (2007-08-28)

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