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Cancer Vaccines Therapy

Reports from H. Lee Moffitt Cancer Center add new data to research in cancer vaccines therapy

Published in Cancer Weekly, August 28th, 2007

Current study results from the report, "Review: anti-CTLA-4 antibody ipilimumab: case studies of clinical response and immune-related adverse events," have been published. According to recent research from the United States, "The immune system is a powerful natural agent against cancer. Cytotoxic T lymphocyte antigen 4 (CTLA-4), a key negative regulator of T-cell responses, can restrict the antitumor immune response."

"Ipilimumab (MDX-010) is a fully human, monoclonal antibody that overcomes CTLA-4-mediated T-cell suppression to enhance the immune response against tumors. Preclinical and early clinical studies of patients with advanced melanoma show that ipilimumab...

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