Angiogenesis
Researchers at St. Jude Children's Research Hospital, Department of Surgery release new data on angiogenesis
Published in Cancer Weekly, September 4th, 2007
Fresh data on angiogenesis are presented in the report "Bortezomib inhibits angiogenesis and reduces tumor burden in a murine model of neuroblastoma. Bortezomib is a proteasome inhibitor with pleiotropic antitumor activity. Here we investigate the antiangiogenic and antitumor efficacy of bortezomib against neuroblastoma both in vitro and in a murine model of localized and disseminated disease," scientists in the United States report.
"In vitro activity of bortezomib was assessed by evaluating its effect on cell proliferation and cell cycle status. Localized tumor burden was followed with caliper measurements and total-body bioluminescence in mice with disseminated...
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Source: Cancer Weekly (2007-09-04)
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