Ovarian Cancer Prognosis

Researchers at Karolinska University, Karolinska Institute have published new data on ovarian cancer prognosis

Published in Cancer Weekly, September 11th, 2007

Investigators publish new data in the report "Analysis of HLA class I-II haplotype frequency and segregation in a cohort of patients with advanced stage ovarian cancer. In solid tumors, human leucocyte antigen (HLA)-A2 has been suggested to be a risk factor and a negative prognostic factor. The HLA-A2 allele in Scandinavia has a high prevalence; it decreases with latitude and also with ovarian cancer mortality in Europe," investigators in Stockholm, Sweden report.

"Furthermore, an association of the HLA-A2 allele with severe prognosis in serous adenocarcinoma of the ovary in stages III-IV was found. Thirty-two unrelated Swedish women with relapsing or progressive...

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Source: Cancer Weekly (2007-09-11)

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