Colon Cancer

New colon cancer data have been reported by researchers at Aarhus University

Published in Cancer Weekly, September 11th, 2007

According to recent research published in the journal Molecular & Cellular Proteomics, "The gene Clusterin is a target for cancer therapy in clinical trials. The indication for intervention is up-regulated Clusterin expression."

"Clusterin has been reported to be deregulated in multiple cancer types, including colorectal cancer (CRC). However, for CRC the studies have disagreed on whether Clusterin is up- or down-regulated by neoplastic cells. In the present study we sought to clarify the expression and distribution of Clusterin mRNAs and proteins in normal and neoplastic colorectal tissue through laser microdissection, variant-specific real time RT-PCR,...

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Source: Cancer Weekly (2007-09-11)

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