Myeloma

Research by C. Largo and colleagues in myeloma provides new insights

Published in Cancer Weekly, September 11th, 2007

"Multiple myeloma (MM) is a malignant plasma cell neoplasia in which genetic studies have shown that genomic changes may affect almost all chromosomes, as shown by fluorescence in situ hybridization (FISH) and comparative genomic hybridization (CGH). Our objective was the genomic characterization of CD 138 positive primary MM samples by means of a high resolution array CGH platform," scientists in Madrid, Spain report.

"and Methods For the first time, a high resolution array CGH with more than 40,000 probes, has been used to analyze 26 primary MM samples after the enrichment of CD138-positive plasma cells. Results This approach identified copy number imbalances in all...

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Source: Cancer Weekly (2007-09-11)

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