Cancer Vaccines

M.D. Anderson-led team reports possible key to autoimmune disease

Published in Cancer Weekly, October 2nd, 2007

A human peptide that acts as a natural antibiotic against invading microbes can also bind to the body’s own DNA and trigger an immune response in the absence of an infection, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports in an early online publication in Nature.

“This combination of the peptide and self-DNA activates the same immune response pathway as a virus does,” says senior author Michel Gilliet, M.D., assistant professor in M. D. Anderson’s Departments of Immunology and Melanoma Medical Oncology.

Researchers believe this response is both a likely key driver of autoimmune disease and an...

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Source: Cancer Weekly (2007-10-02)

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