Endometrial Cancer

Study results from University of New Mexico in the area of endometrial cancer published

Published in Cancer Weekly, October 2nd, 2007

According to recent research from the United States, "Endometrial cancer models are critical to the advancement of investigation, and Ishikawa H and Hec50co cells have been used as research tools. The purpose of these studies is to verify the degree to which these commonly used cell models share the molecular characteristics of the two major in vivo endometrial cancer subtypes, I and II."

"The studies reported include an analysis of pathologic features, tumor suppressor mutations, detailed karyotyping, and cell cycle regulation. Ishikawa H cells are hormone responsive and have lost PTEN expression. In addition they have lost RBI expression due to a deletion in exon 9....

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Source: Cancer Weekly (2007-10-02)

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