Breast Cancer Therapy
Researchers from Catalan Institute of Oncology provide details of new studies and findings in the area of breast cancer therapy
Published in Cancer Weekly, November 6th, 2007
Data detailed in 'Inhibition of Fatty Acid Synthase (FASN) synergistically enhances the efficacy of 5-fluorouracil in breast carcinoma cells' have been presented. "The lipogenic enzyme fatty acid synthase (FASN) is differentially overexpressed and hyperactivated in a biologically aggressive subset of breast carcinomas and minimally in most normal adult tissues, rendering it an interesting target for anti-neoplastic therapy development. We previously reported that the FASN blockade can induce a synergistic chemosensitization of breast cancer cells to microtubule interfering agents (MIAs) such as docetaxel, paclitaxel and vinorelbine," scientists in Spain report.
"Upon...
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Source: Cancer Weekly (2007-11-06)
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