Published in Cancer Weekly, November 6th, 2007
"Whereas the tumour suppressor functions for p16(INK4a) and p14(ARF) have been firmly established, the role of p15(INK4b) remains ambiguous. However, many 9p21 deletions also remove CDKN2b, so we hypothesized a synergistic effect of the combined deficiency for p15(INK4b), p14(ARF) and p16(INK4a). Here we report that mice...
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