Cancer Gene Therapy
Investigators at University of Navarra publish new data on cancer gene therapy
Published in Cancer Weekly, November 27th, 2007
According to recent research from Pamplona, Spain, "Better understanding of the mechanisms that mediate spontaneous immune rejections ought to be important in the quest for improvements in immunotherapy of cancer. A set of intraperitoneal tumors of mesenchymal origin that had been chemically induced in ubiquitously expressing EGFP transgenic mice provided a model in which both T and NK cells were absolutely required for tumor rejection."
"Tumor cells were traceable because of being fluorescent and readily grafted in RAG1(-/-) immunodeficient mice, whereas they were rejected in a majority of syngeneic C57BL/6 and EGFP-transgenic mice. Tumor-cell clones with the highest...
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Source: Cancer Weekly (2007-11-27)
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