Cancer Gene Therapy

New cancer gene therapy study findings have been published by scientists at University of Alabama

Published in Cancer Weekly, November 27th, 2007

"Alternative and complementary therapeutic strategies need to be developed for metastatic breast cancer. Virotherapy is a novel therapeutic approach for the treatment of cancer in which the replicating virus itself is the anticancer agent," researchers in the United States report.

"However, the success of virotherapy has been limited due to inefficient virus delivery to the tumor site. The present study addresses the utility of human mesenchymal stem cells (hMSCs) as intermediate carriers for conditionally replicating adenoviruses (CRAds) to target metastatic breast cancer in vivo. HMSC were transduced with CRAds. We used a SCID mouse xenograft model to examine the...

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Source: Cancer Weekly (2007-11-27)

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