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Breast Cancer

Scientists at Medical University of Vienna detail research in breast cancer

Published in Cancer Weekly, November 27th, 2007

"Purpose In human epidermal growth factor 2 (HER-2)-positive advanced breast cancer, taxanes or vinorelbine plus trastuzumab are among the most widely applied options in the first- line setting. We evaluated the efficacy and tolerability of capecitabine plus trastuzumab after anthracycline and docetaxel or vinorelbine failure and prior trastuzumab exposure," scientists in Vienna, Austria report.

"Patients and Methods Forty consecutive patients were included. Capecitabine was administered at a dose of 1,250 mg/m(2) bid for 14 consecutive days in 3-week cycles, with dose modifications if necessary. Trastuzumab was administered every 3 weeks. Time to progression ( TTP) was...

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