Angiogenesis
Research Uncovers Molecular Function of Endosialin Target of MORAb-004, Anti-Angiogenic Antibody Being Evaluated for Cancer, Neovascular Disease
Published in Cancer Weekly, December 4th, 2007
Morphotek, Inc. announced that a scientific paper published in the recent issue of The Proceedings of the National Academy of Sciences, sheds new light on the biological role of endosialin, also called TEM1, in promoting angiogenesis and tumor growth. Endosialin/TEM1 is a target of one of Morphotek's therapeutic antibody programs. The article, titled "Interaction of Endosialin/TEM1 with Extra-cellular Matrix Proteins Mediates Adhesion and Cell Migration," reports on a study performed by Morphotek researchers about the role of endosialin/TEM1 in neovascular biology.
Experimental data showed that endosialin/TEM1, which has been previously shown to be expressed on cells of...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2007-12-04)
More Articles from Cancer Weekly
- Breast Cancer
First-ever 'State of Breast Cancer Report' Outlines Progress Made, Remaining Challenges in Screening, Diagnosing, Treating, Preventing Top Cancer Killer - Cancer Gene Therapy
New findings from S.O. Freytag and co-authors describe advances in cancer gene therapy - Cancer Gene Therapy
Research from Children's Hospital provides new data about cancer gene therapy - Cancer Gene Therapy
Research from University of Navarra in the area of cancer gene therapy described - Cancer Vaccines
New research on cancer vaccines from Osaka University summarized - Cancer Vaccines
St. Jude Finds Molecule That Could Improve Cancer Vaccine and Therapy for Other Diseases - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
