Cancer Gene Therapy
New findings from S.O. Freytag and co-authors describe advances in cancer gene therapy
Published in Cancer Weekly, December 4th, 2007
"In preparation for a Phase I trial, we evaluated the efficacy and toxicity of replication-competent adenovirusmediated suicide gene therapy in combination with radiation in a preclinical model of pancreatic cancer. Human MiaPaCa-2 and PANC-1 pancreatic adenocarcinoma cells were found to be sensitive to the oncolytic effects of the Ad5-yCD/mutTK(SR39) rep-ADP adenovirus and also to the cytotoxic effects of the yeast cytosine deaminase ( yCD) and herpes simplex virus thymidine kinase ( HSV- 1 TKSR39) genes in vitro," scientists writing in the journal Molecular Therapy report.
"Combining Ad5yCD/ mutTK(SR39) rep-ADP-mediated suicide gene therapy with radiation...
Want to see the full article?
We're a pay-per-view site for premium content. If you'd like to purchase this article, it's only $3.00.
Welcome to NewsRx!
Learn more about a six-week, no-risk free trial of Cancer Weekly
Source: Cancer Weekly (2007-12-04)
More Articles from Cancer Weekly
- Angiogenesis
Research Uncovers Molecular Function of Endosialin Target of MORAb-004, Anti-Angiogenic Antibody Being Evaluated for Cancer, Neovascular Disease - Breast Cancer
First-ever 'State of Breast Cancer Report' Outlines Progress Made, Remaining Challenges in Screening, Diagnosing, Treating, Preventing Top Cancer Killer - Cancer Gene Therapy
Research from Children's Hospital provides new data about cancer gene therapy - Cancer Gene Therapy
Research from University of Navarra in the area of cancer gene therapy described - Cancer Vaccines
New research on cancer vaccines from Osaka University summarized - Cancer Vaccines
St. Jude Finds Molecule That Could Improve Cancer Vaccine and Therapy for Other Diseases - More from this issue of Cancer Weekly
NewsRx is Social
Follow us on your favorite social network by clicking on a button below:
Top Medical Newsletters
Awards
Best Health/Healthcare Content, 2012
Best Health/Healthcare Content, 2011
Best e-Business Site, 2010
Best e-Business Site, 2009
Best e-Business Site, 2008
Best e-Business Site, 2007
Best e-Business Site, 2006
Best Healthcare Content, 2005
Best Overall Internet Site, 2005
Best Interactive Site, 2005
Facts & Stats
NewsRx also is available at LexisNexis, Gale, ProQuest, Factiva, Dialog, Thomson Reuters, NewsEdge, and Dow Jones.
- Google 2010 PageRank: #2 Among Top Health News and Media Publications
- Google 2010 PageRank: #2 Among Top Science Publications in Biology/Physiology
- Google 2010 PageRank: #2 Among Top News and Media for the Business of Pharmaceuticals
- Amazon's Alexa 2010 PageRank: #2 News and Media Site for the Pharmaceutical Industry
