Cancer Gene Therapy

Research from Children's Hospital provides new data about cancer gene therapy

Published in Cancer Weekly, December 4th, 2007

According to recent research from the United States, "Recent studies have shown that germ-fine determination occurs early in development and that extracellular signaling can alter this fate. This denial of a cell's fate by counteracting its intrinsic signaling pathways through extrinsic stimulation is believed to be associated with oncogenesis."

"Using specific populations of multipotent skeletal muscle-derived stem cells (MDSCs), we have been able to generate tumors by subjecting cells with specific lineage predilections to concomitant differentiation signals. More specifically, when a stem cell that had a predilection toward osteogenesis was implanted into a skeletal...

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Source: Cancer Weekly (2007-12-04)

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