Breast Cancer
Scientists at University of California publish research in breast cancer
Published in Cancer Weekly, December 4th, 2007
According to recent research from the United States, "Exposure to beta-Hexachlorocyclohexane ( beta-HCH), a contaminant of the hexachlorohexane pesticide lindane, has been implicated as a risk factor in the development of breast cancers in epidemiological studies. Previous studies in our laboratory have demonstrated the ability of beta-HCH to elicit its actions via a ligand-independent activation of the estrogen receptor through increased c-Neu (= erbB(2) or HER-2) expression and kinase activation in both the BG-1 and MCF-7 cell lines."
"In addition, long term exposure ( 33 passages) to beta-HCH was shown to promote the selection of MCF-7 cells which exhibit a more...
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Source: Cancer Weekly (2007-12-04)
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