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B-Cell Lymphoma
Data on B-cell lymphoma described by researchers at Sun Yat-Sen University
December 18th, 2007
"To date, the biological significance of breast cancer resistance protein (BCRP) G34A and C421A polymorphisms is largely unknown. Analysis of these two polymorphisms in 156 diffuse large B-cell lymphoma (DLBCL) patients and 376 control subjects revealed an increased risk of DLBCL associated with variant BCRP 421 genotypes (CA and AA), when compared with the wild-type CC genotype [odds ratio = 1.49, 95% confidence interval (CI) 1.02-2.17, P = 0.042]," scientists in People's Republic of China report. "Moreover, the increased risk was more evident in younger patients (<= 50 years, odds ratio = 2.14, 95% CI 1.25-3.68,P = 0.006). Further evaluation for the association of...
Source: Cancer Weekly (2007-12-18)
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