Cancer Weekly
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Cancer Vaccines
Research in the area of cancer vaccines reported from Rockefeller University
December 18th, 2007
According to recent research from the United States, "The ultimate goal of most anti-tumor therapies is to kill tumor cells. While most of the attention in cancer therapy has been towards enhancing the death of tumor cells, the effect of dying tumors on the immune system has been less studied." "Recent studies have suggested that cell death induced by different agents may have distinct consequences for the immune system. One of the immunogenic signals may be the expression of heat shock proteins on dying tumor cells under certain settings. For example, bortezomib (a proteasome inhibitor) induces the expression of heat shock protein 90 (hsp90) on the surface of dying...
Source: Cancer Weekly (2007-12-18)
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