Cancer Weekly
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Bladder Cancer
Reports outline bladder cancer research from University of Zurich
December 18th, 2007
"The aim of this study was to investigate STK15 amplification in histologically benign urothelium and invasive tumor tissue of urothelial bladder cancer patients in relation to clinicopathologic and molecular characteristics, and to analyze a hypothesized association between the STK15 single nucleotide polymorphism at site T91A (Phe31Ile) and STK15 gene amplification. A tissue microarray (TMA) was constructed and contained formalin-fixed paraffin-embedded tumor tissue and matching histologically benign urothelium of 44 patients who underwent cystectomy for invasive urothelial carcinoma," investigators in Zurich, Switzerland report. "Expression of TP53, CK20 and MIB1 was...
Source: Cancer Weekly (2007-12-18)
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