Cancer Weekly
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Breast Cancer
Studies in the area of breast cancer reported from O. Kovalchuk and co-researchers
December 18th, 2007
"Breast cancer is the most common malignancy in women continuing to rise worldwide. Breast cancer emerges through a multi-step process, encompassing progressive changes from a normal cell to hyperplasia (with and without atypia), carcinoma in situ, invasive carcinoma, and metastasis," scientists in the United States report. "In the current study, we analyzed the morphological changes and alterations of DNA methylation, histone methylation and microRNA expression during estradiol-17 beta (E-2)-induced mammary carcinogenesis in female August Copenhagen Irish (ACI) rats. E-2-induced breast carcinogenesis in ACI rats provides a physiologically relevant and genetically...
Source: Cancer Weekly (2007-12-18)
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