Prostate Cancer

New prostate cancer study findings have been reported from K. Wiebalk et al

Published in Cancer Weekly, December 25th, 2007

"Repair of radiation-induced DNA damage is believed to play a critical role in developing adverse reactions during radiotherapy. Ionizing radiation induces transcription of several DNA repair genes including XPC as a part of the p53-transmitted stress response," scientists in Heidelberg, Germany report.

"XPC gene induction was measured to analyze whether it predicts occurrence of therapy-related acute side effects. Prostate cancer patients (n = 406) receiving radiotherapy were monitored for development of acute adverse effects using common toxicity criteria. For gene induction analysis, lymphocytes from 99 patients were selected according to their observed grade of...

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Source: Cancer Weekly (2007-12-25)

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