Prostate Cancer

New prostate cancer study findings recently were reported by A.J. Vickers and co-researchers

Published in Cancer Weekly, December 25th, 2007

"Both benign and malignant prostate diseases elevate total prostate-specific antigen (tPSA), and the incidence of benign disease increases markedly with age. There is evidence, however, that free-to-total PSA ratio (%fPSA) and human kallikrein 2 (hK2) more closely reflect the malignant process," scientists writing in the International Journal of Cancer report.

"We tested the hypothesis that tPSA levels are more strongly predictive of cancer in younger when compared to older men, whereas %fPSA and hK2 are more strongly predictive in men tested closer to diagnosis. The study included 13,676 men age >= 44 in Sweden, where PSA screening was uncommon during the...

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Source: Cancer Weekly (2007-12-25)

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