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Cancer Vaccines
Researchers from German Cancer Research Center report on findings in cancer vaccines
January 15th, 2008
Researchers detail in 'Thymus repopulation after allogeneic reconstitution in hematological malignancies,' new data in cancer. "Active vaccination in the allogeneically reconstituted tumor-bearing host essentially requires donor T-cell tolerance. To create a basis for vaccination in the allogeneically reconstituted, lymphoma-bearing host, we elaborate a reconstitution protocol that supports thymus repopulation and tolerance induction," scientists in Heidelberg, Germany report. "Myeloreductively conditioned, lymphoma-bearing mice were vaccinated after reconstitution with hematopoietic progenitor cells. Readout systems included recovery of donor-derived T cells, graft vs...
Source: Cancer Weekly (2008-01-15)
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