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Cancer Weekly

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Apoptosis



Data on apoptosis detailed by researchers at University of Georgia



January 15th, 2008

"Genistein (G) and resveratrol (R) individually inhibit adipogenesis in 3T3-L1 adipocytes and induce apoptosis in cancer cells. We investigated whether the combination of G and R resulted in enhanced effects on adipogenesis, lipolysis, and apoptosis in 3T3-L1 cells," scientists in the United States report.

"Preadipocytes and mature adipocytes were treated with G and R individually at 50 and 100 mu mol/L (G100; R100) and in combination. Both in preadipocytes and mature adipocytes, G and R individually decreased cell viability dose-dependently, but G100 + R100 further decreased viability by 59 +/- 0.97% (P <0.001)and 69.7 +/- 1.2% (P < 0.001) after 48 h compared...


Source: Cancer Weekly (2008-01-15)

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