Cancer Weekly
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Breast Cancer
New breast cancer research reported from Utah State University
January 15th, 2008
"We used Affymetrix microarrays to compare gene expression profiles of the metastatic parental breast cancer cell line MDA-MB-435 (435) and the non-metastatic daughter cell line created by the stable expression of the BReast cancer Metastasis Suppressor 1 (BRMS1) gene in 435 cells, MDA-MB-435-BRMS1 (435/BRMS1). Analysis of microarray data provided insight into some of the potential mechanisms by which BRMS1 inhibits tumor formation at secondary sites," scientists writing in the journal Clinical & Experimental Metastasis report. "Furthermore, due to the importance of the microenvironment, we also examined gene expression under different growth conditions (i.e.,...
Source: Cancer Weekly (2008-01-15)
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