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Retinoblastoma Gene Therapy

Study data from University of Miami, Bascom Palmer Eye Institute update knowledge of retinoblastoma gene therapy

Published in Cancer Weekly, January 29th, 2008

Fresh data on retinoblastoma are presented in the report 'Mechanism of retinoblastoma tumor cell death after focal chemotherapy, radiation, and vascular targeting therapy in a mouse model.' In this recent study, researchers in the United States conducted a study "To evaluate the mechanism and timing of retinal tumor cell death in the LH(BETA)T(AG) mouse model of retinoblastoma after treatment with vascular targeting therapies and conventional therapies (focal chemotherapy and radiation). For vascular targeting therapy, 12-or 16-week-old mice were treated with a single subconjunctival injection of either anecortave acetate (300 microg) or combretastatin A4 (1.5 mg)."

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