Clinical Oncology

Research in the area of clinical oncology reported from University of Texas

Published in Cancer Weekly, January 29th, 2008

"Purpose The BRCAPRO model, used to predict a family's likelihood of carrying a BRCA1 or BRCA2 mutation, was designed using mutation frequencies of white and Ashkenazi Jewish populations, and may not be applicable to other populations. BRCAPRO was recently validated in African Americans, although has yet to be examined in Hispanics," researchers in the United States report.

"This retrospective study reports the mutation frequency and spectrum of BRCA1 and BRCA2 mutations in a Hispanic population and evaluates the BRCAPRO model in Hispanics. Patients and Methods A descriptive analysis of mutation frequency and spectrum was performed for Hispanic patients who underwent...

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Source: Cancer Weekly (2008-01-29)

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